During this on-demand webinar, hear about Merck & Co. Inc. (also known as Merck, Sharp & Dohme) and their experience as we present data on using a 50 L Thermo Scientific DynaDrive Single-Use Bioreactor (S.U.B.) in a high-demand perfusion process. You will see how the DynaDrive S.U.B. can achieve high cell densities (>200 x 106 cells/mL) at low gas flow-rates, and it can be further tuned to control for pH and pCO2.
Coupled with ergonomic improvements, high performance without customization requirements, and the ability to integrate peripheral process analytical technology (PAT) into the controller and S.U.B., the DynaDrive S.U.B. excels as a ready-made system for tomorrow’s processes.
Learning objectives:
- Learn how the DynaDrive S.U.B. can be suitable for culturing high cell densities (up to 200 x 106 cells/mL) with minimal sparge rates
- Experience the set up and operation of a 50-L DynaDrive S.U. B.
- See updates to the DynaDrive S.U.B. as well as associated performance improvements regarding mass transfer, volume, and scale-up.
Speaker Information:
Kristin O’Neill
Principal Scientist, Upstream Pilot Plant Technologies
Merck
Principal Scientist, Upstream Pilot Plant Technologies
Merck
William Tran
Senior Bioprocess Engineer
Merck
Senior Bioprocess Engineer
Merck